Name: Ibutamoren (MK677) | 50mg/1,5ml
Brand: Pen Peptide
SKU: 370
Availability: InStock

Description

What is Ibutamoren (MK-677)?

Ibutamoren, also known as MK-677, is a compound that acts as a ghrelin receptor agonist and growth hormone (GH) secretion stimulator. Unlike SARMs, Ibutamoren does not interact with androgen receptors, but instead mimics the action of the hormone ghrelin and activates the pituitary gland, leading to increased secretion of growth hormone and IGF-1 (insulin-like growth factor).

The compound is the subject of intensive research aimed at improving sleep, increasing muscle mass, supporting recovery processes and maintaining youth in various physiological conditions. MK677 is a popular choice when the goal is to increase the activity of the GH–IGF-1 axis.

Mechanism of action of Ibutamoren (MK677):

Ibutamoren stimulates growth hormone secretion by activating ghrelin receptors (GHS-R) in the hypothalamus and pituitary gland. This leads to a natural increase in GH and IGF-1 levels in the body, which activates processes such as protein synthesis, cell repair and tissue regeneration.

MK677 does not disrupt cortisol or other hormone levels and has the advantage of sustainably maintaining high growth hormone levels for 24 hours. Due to this characteristic, it is preferred for research purposes aimed at recovery, regeneration and anti-aging protocols.

Potential scientifically supported benefits of Ibutamoren (MK677):

Based on research and observations, Ibutamoren shows the following potential benefits:

Stimulate growth hormone and IGF-1 naturally;
Increase in muscle mass and density, even without changing the training regime;
Improved recovery of tissues and tendons;
Better quality and depth of sleep, through the influence on sleep phases;
Potentially improved bone density and locomotor function;
Preservation of lean musculature in caloric deficit or old age.

MK677 is a preferred molecule for protocols aimed at regeneration, hormonal maintenance and optimization of recovery in various physiological conditions.

Comparison of Ibutamoren (MK677) with other SARMs

Ibutamoren (MK677) is often placed in the same category as SARMs due to its use in research protocols for muscle growth and recovery, but it is not technically a SARM. Instead, MK677 is a ghrelin receptor agonist that stimulates the natural release of growth hormone (GH) and IGF-1 without interacting with androgen receptors. This makes it unique compared to molecules like Ligandrol (LGD-4033), Testolone (RAD-140) and Ostarine (MK2866).

Compared to Ligandrol, which acts directly on androgen receptors to increase muscle mass, MK677 works by increasing growth hormone, resulting in slower but more complete recovery, improved sleep and support for tissue regeneration. While LGD-4033 is preferred for aggressive muscle building, MK677 is used for long-term support and hormonal stabilization.

Compared to RAD-140, which provides a strong anabolic effect and short-term muscle response, MK677 acts more gently, but enhances recovery, sleep and supports tendons, skin and joints through IGF-1 activation. It does not lead to testosterone suppression and can be used in extended research cycles without the need for hormone balance afterwards.

Compared to Ostarine, which is also used for muscle maintenance, MK677 has a broader effect – not only on muscle, but also on sleep, bone density and overall recovery. While MK2866 acts at the receptor level in muscle, MK677 stimulates the entire GH–IGF-1 endocrine axis.

Ibutamoren is often combined with other compounds in research models when aiming for more complete regeneration, improved sleep and hormonal balance, without aggressive androgenic stimulation.