Description

What is Andarine S4?

Andarine (S4) is a selective androgen receptor modulator (SARM) developed to maintain and increase muscle mass, improve strength and support bone structure, without the typical side effects associated with traditional androgenic compounds. The compound was one of the first SARMs developed for scientific research and continues to be among the most researched molecules in this class.

Andarine demonstrates moderate anabolic action, with high selectivity for muscle and bone tissue, avoiding a strong impact on the prostate and other sensitive systems. This makes it suitable for research protocols focused on body recomposition, recovery after muscle loss and maintenance of physical strength in a reduced hormonal background.

Mechanism of action of Andarine S4:

Andarine S4 binds to androgen receptors in muscle and bone tissue, where it activates genes responsible for protein synthesis and mineral density. Unlike traditional androgen preparations, Andarine does not significantly affect other tissues, such as the prostate, and is not converted to estrogen.

The molecule has a relatively short half-life, which allows finer control of dosage and research cycles. Its action profile is balanced – strong enough to observe effects on muscle mass, but also light enough to be suitable for shorter or more moderate protocols.

Potential scientifically supported benefits of Andarine S4:

The following potential effects have been observed in scientific and laboratory studies:

• Increase in lean muscle mass, especially with deficiency or immobilization;
• Improving physical strength and muscle density;
• Maintenance of bone mineralization and resistance;
• Optimizing body composition while simultaneously maintaining muscles;
• Appropriate selectivity to androgen receptors, without strong impact on other systems;
• Subcutaneous formulation stabilized for easy and accurate dosing.

These properties make Andarine S4 the preferred choice in laboratory settings where a controlled effect on muscle and bone function is sought, without risks of unwanted hormonal interactions.

Comparison of Andarine S4 with other SARMs

Andarine (S4) was one of the first SARMs developed and remains well known for its balanced anabolic effect, moderate potency and relatively short half-life. Due to these characteristics, S4 is often compared to Ostarine (MK2866), Ligandrol (LGD-4033) and S23, occupying an intermediate position between the mild and more potent SARMs.

Compared to Ostarine, Andarine shows a stronger effect on physical strength and muscle tissue density, but also with a higher risk of side effects, such as temporary visual disturbances – one of the most distinctive aspects of S4. While Ostarine is preferred in long-term and maintenance research protocols, S4 is used in more intense cycles to increase functional strength and muscle relief.

Compared to Ligandrol, Andarine has a weaker anabolic effect, but also a shorter duration of action, which allows for more precise dosage adjustment. LGD-4033 outperforms S4 in gaining lean mass, while S4 has shown excellent results in protocols focused on preserving muscle tissue in a caloric deficit and improving density and definition.

Compared to S23, Andarine is significantly safer, with less suppression of endogenous testosterone, but also with a more moderate anabolic effect. S23 often requires close monitoring and post-protocol hormonal support, while S4 has been successfully administered under more lightly controlled conditions.

Dosage and administration of Andarine S4 in research protocols:

Recommended study schedule: 3 units twice daily (6 units total per day), for 2–4 weeks, followed by a 4–6 week rest period.

1 unit = 26.66mcg.

Total quantity in pen: 150 units

Possible side effects of Andarine S4:

Despite its widespread use in laboratory models, there are observations of some side effects, especially with prolonged use or higher doses:

• Changes in the perception of colors (yellowish tint) – reversible when the intake is stopped;
• Temporary suppression of natural testosterone in longer cycles;
• Individual sensitivity to androgen stimulation.

Compliance with the optimal dosage and control over the duration of the application play a key role in limiting the manifestation of side effects.

For laboratory purposes and personal observation only.